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| This is an operative photograph from the pancreas surgery collection of Dr. Ilango Sethu, one of our senior consultants in pancreatic oncology and oncosurgery. The patient is a 60 year old gentleman with cancer in the head of the pancreas. He was diagnosed to have pancreatic cancer during the evaluation of jaundice. The patient had a high risk of heart attack and could not be treated by angioplasty. So he underwent coronary bypass surgery after stenting (small net like structure seen on the right of the yellow colored loop). After recovering from the coronary bypass surgery, the patient has undergone a Whipple's operation with resection of the superior mesenteric vein. The photograph above shows how the vein was separated and removed along with the tumour. This vein was stitched back again and the blood flow to the liver was restored. Such technical advancements can provide good life to patients with pancreatic cancer. Today, we combine such treatments with the state of the art chemotherapy regimens called FOLFIRINOX to prolong life and hope for patients with pancreatic cancer. |
CA 19.9 is an essential part of the evaluation of pancreatic cancer. CA stands for Carbohydrate antigen. This CA19.9 is normally produced in two sources in the human body - pancreatic parenchymal cells and the biliary epithelial cells. We still don't know the connection points between the tissue production of CA19.9 and the blood levels. This protein was discovered in the research for large intestinal cancers, but we have found that it is very useful in pancreatic malignancies. A level of > 1000 has a very high chance (around 99%) of pancreatic cancer. The normal level is around 37 U/L and usually the other cutoffs that pancreatic surgeons remember is 100 U/l and 500 u/L, to assess cancer diagnosis and features of advancing disease. It is important to check your CA 19.9 levels after the jaundice is relieved by ERCP and stenting. High levels in the presence of jaundice or cholangitis (infection of the bile ducts) is not useful to assess advanced disease. At PCRRC, we keep 500 u/L...


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